Time/Day Monday
June 6, 2022
Tuesday
June 7, 2022
Wednesday
June 8, 2022
Thursday
June 9, 2022
Friday
June 10, 2022
Saturday
June 11, 2022
8:30-9:30 General in vitro cytotoxicity and cell death assays – Mathieu Vinken, Vrije Universiteit Brussel, BelgiumThe use of adverse outcome pathways in in vitro toxicology – Mathieu Vinken, Vrije Universiteit Brussel, Belgium
In vitro methods for skin irritation and corrosion testing – Helena Kandárová,
Slovak Academy of Sciences, Slovakia

In vitro methods for testing genetic toxicity and carcinogenicity – Philippe Vanparys, GENTOXICON, Belgium
Alternative methods and OECD testing guidelines –
Helena Kandárová, Slovak Academy of Sciences, Slovakia
9:30-10:30 Good in vitro method practice (ONLINE) – Sandra Coecke, JRC, Italy In vitro kinetics and in vitro-in vivo extrapolation –
Bas Blaauboer, Utrecht University, The Netherlands
In vitro methods for testing immunotoxicity and skin sensitisation (ONLINE) – Sandra Coecke,
JRC, Italy 
Group exercise Plenary discussion
10:30-11:00 BreakBreakBreakBreakBreak
11:00-12:00  Current practices for the validation of in vitro methods (ONLINE) – Sandra Coecke, JRC, Italy PBK modelling and quantitative in vitro-in vivo extrapolation (QIVIVE), Jochem Louisse, Wageningen Food Safety Research, The NetherlandsIn vitro toxicology testing of nanomaterials –
Arno Gutleb, Luxembourg Institute of Science and Technology, Luxembourg
Group exerciseWritten Exam
12:00-13:00 Lunch Break Lunch Break Lunch Break Lunch Break Lunch Break 
13:00-14:00 Liver-based in vitro models for toxicology purposes –
Mathieu Vinken, Vrije Universiteit Brussel, Belgium
In vitro methods for testing developmental toxicity –
Ellen Fritsche, Leibniz Research Institute for Environmental Medicine, Germany

Lung-based in vitro models for toxicology purposes –
Arno Gutleb, Luxembourg Institute of Science and Technology, Luxembourg
Group exerciseAdjourn
14:00-15:00Gastro-intestinal in vitro models for toxicology purposes –
Meike van der Zande, Wageningen Food Safety Research, The Netherlands
In vitro methods for eye hazard testing –
Helena Kandárová, Slovak Academy of Sciences, Slovakia
The use of ‘omics’ in in vitro toxicology –
Theo de Kok, Maastricht University, The Netherlands
  Group exercise
15:00-15:30 BreakBreakBreak   
15:30 – 17:30Registration starts from 16:00

Novotel Luxembourg Centre
35, rue du Laboratoire
L‐1911 LUXEMBOURG

(10 min walking distance from
the IBIS hotel)
Hands-on training I
Introduction into in vitro 3D tissue models engineering –
Arno Gutleb & team,
LIST, Luxembourg

Hands-on training II
In vitro gastro-intestinal toxicity testing with 3D models –
Jan Markus,
MatTek Life Sciences/BICO group Slovakia Slovakia
Hands-on training III
In vitro eye irritation testing with 3D cornea models –
Silvia Letašiová, MatTek Life Sciences/BICO group Slovakia



Hands-on training IV
Introduction into the microfluidic work
Silvia Scaglione
React4Life, Italy


Hands-on training V
Introduction into the Human on the Chip/Organ on a chip work
Isabel Rütschle
TissUse, Berlin, Germany


Hands-on training VI – 3D printing introduction and demonstration,
Diana Cervantes
Cellnk, Gothenburg, Sweden

Hands-on training VII
Inhalation toxicity testing with advanced equipment (Vitrocell)
Arno Gutleb & team,
LIST, Luxembourg
Luxembourg
17:30 – ….Course introduction,
Ice- breaking event
starts at 17:30

Location:

Novotel Luxembourg Centre
35, rue du Laboratoire
L‐1911 LUXEMBOURG

(10 min walking distance from
the IBIS hotel)

 Guided tour at 18:00

Luxembourg City Tourism Office
30, Place Guillaume II
L‐1648 Luxembourg


Social event at 19:00
Restaurant
L’Osteria

8, place Guillaume II
L‐1648 Luxembourg