The ESTIV Members Area| me/Day | Sunday November 24, 2024 | Monday November 25, 2024 | Tuesday November 26, 2024 | Wednesday November 27, 2024 | Thursday November 28, 2024 | Friday November 29, 2024 |
| 8:30-9:30 | General in vitro cytotoxicity and cell death assays – Helena Kandárová, Slovak Academy of Sciences, Slovakia | Alternative methods and OECD testing guidelines – Helena Kandárová, Slovak Academy of Sciences, Slovakia | Stem cell-based brain organoid models. Jens Schwamborn, University Luxembourg and ORGANOTHERAPEUTICS | PBK modelling and quantitative in vitro-in vivo extrapolation (QIVIVE). Susana Proenca, esqLabs | In vitro methods for testing genetic toxicity and carcinogenicity – Philippe Vanparys, GENTOXICON, Belgium | |
| 9:30-10:30 | Introduction to adverse outcome pathways in in vitro toxicology. Luiz Ladeira, University of Liège, Belgium | In vitro methods for skin irritation and corrosion testing – Helena Kandárová, Slovak Academy of Sciences, Slovakia | Respiratory sensitization: current status of in vitro models. Sabina Burla, INVITROLIZE, Luxembourg | Development and implementation of new approach methodologies in genetic toxicology. Giel Hendriks, Toxys | Group exercise | |
| 10:30-11:00 | Break | Break | Break | Break | Break | |
| 11:00-12:00 | Good in vitro method practice (GIVIMP and OECD GLP) Helena Kandárová, Slovak Academy of Sciences, Slovakia | In vitro methods for testing immunotoxicity and skin sensitisation – t.b.c. Sandra Coecke, JRC, Italy (ONLINE) | Pitfalls of in vitro testing. Emma Arnesdotter, LIST, Luxembourg | Animal-product free cell culture: status and challenges. Pamina Weber/Aline Chary, LIST, Luxembourg | Group exercise | |
| 12:00-13:00 | Lunch Break | Lunch Break | Lunch Break | Lunch Break | ||
| 13:00-14:00 | Liver-based in vitro models for toxicology purposes – Mathieu Vinken, Vrije Universiteit Brussel, Belgium (ONLINE) | Lung-based in vitro models for toxicology purposes – Arno Gutleb, Luxembourg Institute of Science and Technology, Luxembourg | The use of ‘omics’ in in vitro toxicology – Theo de Kok, Maastricht University, The Netherlands | In vitro kinetics and in vitro-in vivo extrapolation. Bas Blaauboer, Utrecht University, The Netherlands | Group exercise | |
| 14:00-15:00 | In vitro toxicology testing of nanomaterials. Tommaso Serchi, LIST, Luxembourg | Gastro-intestinal in vitro models for toxicology purposes – Jan Markus, MatTek Life Sciences/BICO group Slovakia Slovakia | In vitro methods for eye hazard testing – Helena Kandárová, Slovak Academy of Sciences, Slovakia | Concepts in microfluidics. Tomasso Sbrana, IVTech, Italy | Group exercise | |
| 15:00-15:30 | Break | Break | Break | |||
| 15:30 – 17:30 | Registration starts from 15:30-16:00 Location: IBIS Hotel Belval | Hands-on training I 3D-model assembly and Vitrocell systems for inhalation toxicity testing. Servane Contal, Sabina Burla, LIST, INVITROLIZE, Luxembourg | Hands-on training II In vitro gastro-intestinal toxicity testing with 3D models – Jan Markus, MatTek Life Sciences/BICO group Slovakia Slovakia | Hands-on training III In vitro eye irritation testing with 3D cornea models – Marek Puškár, MatTek Life Sciences/BICO group Slovakia | Hands-on training IV Introduction into the microfluidic work. Tommaso Sbrana, IVTech, Italy | Written Exam |
| 16:00-17:30 Course introduction Participant Introduction | Guided tour at 18:45 in Luxembourg Social event at 20:00 Dinner in Luxembourg City | End of the course Adjourn |
Hands-on training V
Introduction into the Human on the Chip/Organ on a chip work , Hands-on training VI – 3D printing introduction and demonstration, Hands-on training V
Introduction into the Human on the Chip/Organ on a chip work